Compound database
Curated longevity compounds — with studies, dosage guidance, and matching products. Affiliate links transparently labeled.
Ashwagandha (KSM-66)
Adaptogen with solid RCT evidence for cortisol reduction, sleep quality, and perceived stress.
Berberine (HCl, dihydroberberine)
Plant alkaloid with metabolic effects — lowers fasting glucose and LDL in multiple meta-analyses. Drug interactions exist.
Fisetin
Flavonoid with senolytic activity in animal models. Clinical endpoints in humans still unclear.
Glycine
Amino acid with effects on sleep quality, core body temperature, and methylation. Inexpensive and well studied.
Creatine Monohydrate
One of the most thoroughly studied supplements. Benefits for muscle, bone, and increasingly cognition.
Magnesium Glycinate
Highly bioavailable, gentle on the stomach. Supports sleep, muscle recovery, and neural function.
NMN (Nicotinamide Mononucleotide)
Direct NAD+ precursor. Early-phase clinical evidence shows raised blood NAD+ levels after oral dosing.
Omega-3 Fish Oil (EPA/DHA)
Lowers triglycerides, modulates inflammation. Relevant for anyone not eating fatty fish regularly.
Quercetin (with bromelain)
Flavonoid with anti-inflammatory and senolytic properties (studied alongside dasatinib). Poor oral bioavailability.
Spermidine (from wheat germ)
Polyamine with autophagy-inducing effects in vivo. Early-phase human data on cognition and mortality in cohorts.
Taurine
Conditionally essential amino acid with promising animal data on lifespan extension. Human data is emerging.
Vitamin D3 + K2
Vitamin D status is widely insufficient from autumn through spring in temperate climates. K2 complements D3 synergistically.