AdaptogenModerate evidence

Ashwagandha (KSM-66)

Adaptogen with solid RCT evidence for cortisol reduction, sleep quality, and perceived stress.

Also known as: withania-somnifera, ksm-66, sensoril

Goals
SleepStressHormones
Timing
Evening
Price tier
Medium

Dosage

300–600 mg KSM-66 per day, preferably in the evening.

Considerations

Prefer standardized extracts (KSM-66 or Sensoril). Avoid during pregnancy.

VeganDrug interactionsNot during pregnancy
Form
CapsulePowder

Scientific detail

Mechanisms
HPA-Achse ModulationCortisol-SenkungGABA-erge Aktivität
Hallmarks of aging
Altered intercellular communication
Evidence base

Studies on Ashwagandha (KSM-66)

1,975 studies total · Open on PubMed

View all studies →
25
Sleep
51
Stress & anxiety
79
Hormones

Where to buy

Affiliate link — we may earn a commission at no extra cost to you.
View on Amazon DEView on Sunday NaturalView on iHerb