OtherEmerging

Spermidine (from wheat germ)

Polyamine with autophagy-inducing effects in vivo. Early-phase human data on cognition and mortality in cohorts.

Also known as: spermidine

Goals
Longevity (broad)Cognition
Timing
Morning
Price tier
Premium

Dosage

1–6 mg/day, morning. Wheat germ extracts are the standard.

Considerations

Also found in food (cheese, legumes, mushrooms). Supplementation only useful with low dietary intake.

VeganNot during pregnancy
Form
Capsule

Scientific detail

Mechanisms
Autophagie-InduktionHypusinierung von eIF5A
Hallmarks of aging
Disabled macroautophagyMitochondrial dysfunction
Evidence base

Studies on Spermidine (from wheat germ)

10,735 studies total · Open on PubMed

View all studies →
245
Longevity & aging
24
Cognition

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