EssentialModerate evidence

L-Lysine

Essential amino acid — the body cannot synthesise it. Critical for collagen synthesis, calcium absorption, and immune function. Clinically best known for herpes prophylaxis (HSV-1).

Also known as: lysine, lysine-HCl

Goals
ImmuneSkin
Timing
Any time
Price tier
Low

Dosage

Prophylactic 1 g/day, during active HSV outbreak 1–3 g/day. Better bioavailability on an empty stomach.

Considerations

Use caution with kidney impairment. High doses may cause GI upset. Plant-based diets (especially low in legumes) can predispose to lysine deficiency.

Vegan
Form
CapsulePowder

Scientific detail

Mechanisms
Collagen cross-linkingArginine antagonism (HSV)Calcium absorption
Hallmarks of aging
Proteostasis loss
Evidence base

Studies on L-Lysine

91,012 studies total · Open on PubMed

View all studies →
4,447
Immune system
699
Skin
My pick

Currently in my stack:

L-Lysin 2000 mg, 365 Tabletten
VitaminExpress
L-Lysin 2000 mg, 365 Tabletten

Essential amino acid from fermentation, immune support when needed.

Compound details →Amazon

Where to buy

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