AntioxidantModerate evidence

Turmeric (Curcumin)

Polyphenol from turmeric root with potent anti-inflammatory properties. Inhibits NF-κB and multiple inflammatory pathways. Bioavailability is the key challenge — piperine or liposomal formulations significantly improve absorption.

Also known as: curcumin, curcuma longa, diferuloylmethane

Goals
JointsLongevity (broad)Cardiovascular
Timing
With food
Price tier
Low

Dosage

500–2,000 mg curcumin/day, with a fat-containing meal. Combine with piperine (BioPerine®) or use liposomal/phytosomal forms for better bioavailability.

Considerations

Interactions with blood thinners (warfarin, aspirin). Avoid in gallstones and pregnancy. Plain turmeric powder has very low bioavailability (~1 %).

VeganDrug interactionsNot during pregnancy
Form
CapsulePowder

Scientific detail

Mechanisms
NF-κB inhibitionCOX-2 modulationNrf2 activationAMPK activation
Hallmarks of aging
Chronic inflammationMitochondrial dysfunctionDeregulated nutrient sensing
Evidence base

Studies on Turmeric (Curcumin)

30,698 studies total · Open on PubMed

View all studies
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